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PostPosted: Sun Jun 26, 2011 8:47 pm 
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Asian Leopard Cat

Joined: Mon Dec 10, 2007 2:23 pm
Posts: 130
Location: Lancashire/n yorks
Not a lot have been tested yet so the percentage may well drop as more test...
We really need to spread the word as some of the carriers i know of are NOT related to each other at all....

I think there is confusion about PK DEF as some i spoke to last week thought it was the Kidney Disease and they were shocked when they were told more about it. It is a disease we can get rid of in the Bengal worls, but only if people test...

wendy

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PostPosted: Sat Jul 02, 2011 9:10 pm 
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Bengal Kitten

Joined: Thu Jan 15, 2009 12:40 pm
Posts: 23
PK Deficiency - GCCF - UK breeders - please crosspost

On behalf of Steven Robertson:

"Dear Steven

On behalf of the Progressive Singapura Cat Club, I have been in talks with Langford University regarding PK (Def) and they are willing to put together a meeting at Langford to help breeders to understand PK (Def) and have an opportunity for discussions so that they can formulate breeding plans to work the breed out of this problem.

They would have feline medical specialists to talk about the disease, the genetics and inheritance patterns for different matings and also give a large amount of time over to discussion and questions. This would be a golden opportunity to pick the brains of the experts to ensure the future of our breeds.

They would like some idea of how many breeders they would need to cater for and as UK Bengals have recently found PK (Def) in some of their lines, we are extending the invitation to Bengal Breeders as it is so new in your breeds.

I would be grateful if you could get this out to Bengal Breeders and ask them to give me an idea if they would be interested in attending (date to be determined) and would appreciate replies to progressivesingapuracc@gmail.com

I do hope you and others will be able to join us and expand your knowledge of this disease and how to rid our breeds of it without jeopardising the viability of the breed.

Please feel free to forward this email onto any interested parties or groups.

Marcia Owen"

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PostPosted: Mon Jul 04, 2011 10:47 am 
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Asian Leopard Cat

Joined: Wed Jan 02, 2008 12:46 am
Posts: 538
Location: Finland
I have tested three of my cats this summer and I tested only because others told me this was found recently in our breed. There were NO reason to suspect. Nothing. I can´t emphasize in enough, no signs what so ever. Healthy cats, good moms, normal litters.

Lara had two healthy, big litters of kittens and Bertta one litter of three. They have never been sick in their life. They are both screened negatives for HCM and any other heart conditions, they are big, strong, good mothers, wonderful temperaments, they have multiple titles both in FIFE and TICA. Bertta is full adult whited. They were perfect breeding cats and still are perfect pets. And then came this. About 6 weeks ago I had never heard about PK-def, or didin´t know what it really is. Now I know more than I ever wanted.

Lara is positive, she is soon 6 years, I think she is among the oldest bengals tested so far
Bertta, Lara´s daughter is positive soon 3 years old
Aryante is Bertta´s daughter and she is carrier.

Many breeders here in Finland have tested and there are at least 6 carriers from different lines and my two positives. Testing has been selective and there are not enough cats who have been tested, but sure is, this is wide spread.

Good news is, what I have heard from aby and somali breeders, affected cats can live normal life and symptoms are usually mild. many of positives never get sick. This is much better from cat´s point of view than HCM. It is possible to breed from it without narrowing the gene pool. We know it is recessive and we have DNA test. There is no reason for panic.

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PostPosted: Mon Jul 04, 2011 12:13 pm 
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Bengal Kitten

Joined: Sat Sep 13, 2008 7:32 pm
Posts: 1
As soon as I heard about this from Katja I started to test my cats.. And I found out that I have 2 carries at home, and I'm still waiting for more results to come..

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PostPosted: Mon Jul 04, 2011 12:14 pm 
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Bengal Kitten

Joined: Thu Jan 15, 2009 12:40 pm
Posts: 23
There is a new facebook group:

PK-Deficiency and Bengals

https://www.facebook.com/home.php?sk=gr ... 0058980860

Please feel free to join.

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Cattery Ifness, The Netherlands
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PostPosted: Mon Aug 15, 2011 5:09 pm 
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Asian Leopard Cat

Joined: Tue Jan 16, 2007 2:47 pm
Posts: 3609
Location: UK
These are the current figures for Bengals recently tested for PK defic. by the UK lab.

http://www.langfordvets.co.uk/lab_pcr_bengal_pkdef.htm

The figures will be updated as more cats are tested. At the moment the cats tested are mostly breeding cats, however anyone whose cat is sickly or anaemic, it would be worthwhile getting it tested for PK defic. no matter what its age.
Details of the test - http://www.langfordvets.co.uk/laboratory_owners.htm
how to take a mouth swab - http://www.langfordvets.co.uk/lab_pkdsampling.htm#own

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PostPosted: Mon Aug 15, 2011 5:56 pm 
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Asian Leopard Cat

Joined: Tue Jan 12, 2010 8:08 pm
Posts: 2846
Location: West Midlands, UK
Thanks for the information

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PostPosted: Thu Sep 15, 2011 8:20 am 
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Asian Leopard Cat

Joined: Tue Jul 20, 2010 9:09 pm
Posts: 977
Location: Surrey, UK
Hi all

In case none of you have yet seen my other posting, but my little Alfie is to be tested for this as the vet this week suspected FIP, but Alfie's breeder caleld the vet to ask for him to be tested for this as well.

Fingers crossed x

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PostPosted: Tue Oct 25, 2011 6:19 pm 
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Asian Leopard Cat

Joined: Tue Jan 16, 2007 2:47 pm
Posts: 3609
Location: UK
New figures from Langford. 12 Bengal cats have now tested positive ie just over 2% of the breed being tested positive.
27% of those tested are carriers,

http://www.langfordvets.co.uk/lab_pcr_bengal_pkdef.htm

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PostPosted: Tue Oct 25, 2011 10:36 pm 
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Asian Leopard Cat

Joined: Mon Aug 20, 2007 2:54 pm
Posts: 10875
Location: Cumbria, UK
Hi Elaine

Good to see that Langford are publishing the summary stats on their website. Do you know if they include the ones where pet owners have submitted the swabs without vet verification? I know Langford say that if you want the results included in the FAB negative list then they must be submitted via the vet but I'm not clear on whether they get included in their own stats if they're submitted directly?

I've had Dolly tested and I did get the vet to verify the sample (mainly because I wasn't sure I'd actually get any cells on the swab if I did it myself :) ). She came back heterozygous (carrier) which is a good result for me as she's a pet. I'm having Alfie and Merlin tested at the end of November when they have their vaccinations.

Does anyone else do the testing apart from Langford?

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PostPosted: Wed Nov 30, 2011 10:47 pm 
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Asian Leopard Cat

Joined: Mon Aug 20, 2007 2:54 pm
Posts: 10875
Location: Cumbria, UK
Update on Alfie and Merlin - I had them both tested last week when they went for their vaccinations and they've both come back heterozygous (carriers). Dolly was the same when she was tested and as they're all neutered pets, that's a great result for them (and me).

Just shows you that carriers of PKDef must be in a lot of lines as my 3 are all from totally different breeders but I guess we're still talking about a relatively small gene pool overall.

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PostPosted: Thu Dec 08, 2011 11:08 pm 
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Asian Leopard Cat

Joined: Tue Jan 26, 2010 4:04 am
Posts: 721
Location: Colorado, USA
Had this gene not spread into US lines? I am not finding any breeders or any information on anyone over here screening for Pk-Def.


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PostPosted: Thu Dec 08, 2011 11:12 pm 
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Asian Leopard Cat

Joined: Sun Aug 08, 2010 6:12 pm
Posts: 3399
Location: Scotland - Paisley
7Deadly$ins wrote:
Had this gene not spread into US lines? I am not finding any breeders or any information on anyone over here screening for Pk-Def.


I would find it hard to believe, given many of the lines here are actually imported from the US???

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PostPosted: Thu Dec 08, 2011 11:14 pm 
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Asian Leopard Cat

Joined: Tue Jan 26, 2010 4:04 am
Posts: 721
Location: Colorado, USA
Maybe I'll contact some of the breeders I've been in touch with (still don't have a bengal kitten over here...) about it. I was just curious, because even some of the breeders I consider the most proactive healthwise and the most "cutting edge" of Bengal health don't have anything to say about it on their sites.


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PostPosted: Fri Dec 09, 2011 12:58 am 
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Asian Leopard Cat

Joined: Mon Dec 10, 2007 2:23 pm
Posts: 130
Location: Lancashire/n yorks
I believe that the numbers of carriers etc that have been found by UC Davies are very simular to the numbers found by Langford here.. It may just be that some breeders still are not aware.. Its only been a few month since it was first discovered in Bengals in the UK..

wendy

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