It looks like you now have an outdoor bengal. First of all, if there is any change in the behavior of your kitty, a vet should examine the cat to make sure all is well medically. When it comes to bengals and howling, you just have to get used to it. Mine cries to go outside constantly. He was an outdoor cat, but he tends to get beat up by other cats -- pretty severely, so once I took ownership of him, he stays inside and we enjoy daily walks, plus he has an outdoor enclosure that keeps him safe.
Normally, cats do not "retaliate" because they are mad. I have had cats with bad tempers, but my bengal has the sweetest disposition. Most cats prefer to use a litter box. The fact that they used your dresser as a little box could mean they didn't have any way to get to their regular litter box. You know if Izzy meows for you, she meowed when your mom stayed with them and it may have been too much for her and, as Elaine said, she just shut them away for a while.
The fact that you're obviously stressing over this can cause your cats to behave even more erratically. I am not sure what I would do in your situation. I might try to construct something outdoors that would contain at least Izzy so she isn't wandering all over creation and finding trouble or eating something she shouldn't.
Your vet is wrong about no medications for cats with epilepsy. I found this online:
Medications Used to Treat Feline Seizures and/or Epilepsy
Phenobarbital is generally considered to be the first choice in treating feline seizures or epilepsy. Currently, it is the most commonly used anticonvulsant drug in cats.
Benzodiazepine medications such as diazepam (Valium®) can be used effectively to control seizures in cats also. Diazepam can be combined with phenobarbital to treat cats that still have seizures while receiving phenobarbital alone or for cats that require a larger than recommended dose of phenobarbital to control their seizures. The addition of diazepam may allow you to lower the dosage of phenobarbital and obtain better seizure control.
Potassium bromide is a commonly used medication for controlling seizures in dogs. However, in cats, the risk of side effects from using potassium bromide is higher than in dogs. Many veterinarians feel that the risk of side effects is too high to justify the use of potassium bromide in cats.
Levetiracetam (Keppra®) has been used in cats to control seizures and epilepsy. It is a newer anticonvulsant medication that may be an alternative for those cats that do not respond well to phenobarbital and/or diazepam. Some veterinarians are now using levetiracetam as a first choice drug rather than phenobarbital because they believe it may have fewer side effects. However, it has not, as of this time, been studied as thoroughly as phenobarbital.
Medications such as zonisamide, felbamate, pregabalin and gabapentin have not been well-studied in cats. Though some veterinarians do use them to control seizures and epilepsy in cats, there is not a lot known about how these medications affect cats on a long-term basis and what types of side effects to expect. As research continues with these drugs, they may become more widely recommended for cats with seizures and epilepsy.
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