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 Post subject: Bengal Polyneuropathy
PostPosted: Sat May 03, 2008 7:12 pm 
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Asian Leopard Cat

Joined: Sat May 03, 2008 6:52 pm
Posts: 238
Location: Scotland
Hi all,
I was reading about poor 'Sadie not walking properly'.
My little boy Ziggy (13 months old) has been displaying the very same symptoms, such as no power or use of his rear legs and he is very lethargic. He was at the vets on Tuesday for X-rays,bloods etc. Went back on Friday for the results and nothing showed up. The vets where superb. They have never seen a cat act this way before, so they contacted the small animal hospital at Edinburgh University, and played a video clip of Ziggy walking. One of the feline doctors there reckonds it is bengal Polyneuropathy. Ziggy is going through to Edinburgh uni next week for a muscle biopspy. This is the only way that they can identify the cause. This is the third case in Scotland. Fingers and toes crossed that he will be ok.
Has anyone else experienced this in their cats.


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 Post subject:
PostPosted: Sat May 03, 2008 7:29 pm 
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The Boss
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Joined: Thu Jul 01, 2004 1:41 am
Posts: 1240
Have you alerted your breeder to this?

If it is Polyneuropathy they might have experienced problems in other kittens in the past.

I did hear of one a few years ago with similiar symptoms, not sure of the official diagnosis or outcome though.

Please keep us updated on Ziggy's progress!


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 Post subject:
PostPosted: Sat May 03, 2008 7:32 pm 
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Asian Leopard Cat

Joined: Sat May 03, 2008 6:52 pm
Posts: 238
Location: Scotland
Phoned the breeder last night.
As you can guess they are very upset aswell. I will be keeping them and the forum updated with Ziggs.

thanks for your concerns


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 Post subject:
PostPosted: Sat May 03, 2008 9:23 pm 
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Asian Leopard Cat

Joined: Tue Jan 16, 2007 2:47 pm
Posts: 3809
Location: UK
Hi Colin,

Sorry to hear of the problems, how did this all start? Is it a sudden thing or has Ziggy been like this for a while?

_________________
Elaine


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 Post subject:
PostPosted: Sat May 03, 2008 9:34 pm 
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Asian Leopard Cat

Joined: Sat May 03, 2008 6:52 pm
Posts: 238
Location: Scotland
Hi junglerose,
it started last weekend. It was as if Ziggs was lame on his four legs. It is hard to describe how he was walking. It happened really fast. He has no power to his back legs. He cannot climb onto a chair(bless him). He is still happy purring away etc. he is getting lotso f extra loving from us. We are really worried about him. Hopefully the boffins at Ediburgh Uni will find out what is causing this and get him back to near his old self.


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 Post subject:
PostPosted: Sat May 03, 2008 10:09 pm 
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Asian Leopard Cat

Joined: Tue Jan 16, 2007 2:47 pm
Posts: 3809
Location: UK
Hi

I have read that if it is bengal neuropathy then

Quote:
Early age of onset appears to be associated with a higher chance of recovery

http://www.fabcats.org/breeders/inherited_disorders/bengal.php

If it is neuropathy, let's hope the above is right and Ziggy is back to normal soon.
Fingers, toes and everything else crossed for him.

_________________
Elaine


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 Post subject:
PostPosted: Sun May 04, 2008 5:33 pm 
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Asian Leopard Cat

Joined: Thu Mar 20, 2008 1:19 pm
Posts: 1916
Location: Wiltshire, England
Had a case of this a few years ago. Two kittens, litter siblings, at around 5.6 months of age suddenly went off their rear legs. They were sent to Bristol and tested for every imagineable illness, scanned, x-rayed etc. and could not find anything. To all purposes, they were very healthy kittens. Bristol took biopsies and sent them off to the neurological department at La Jolla, California. The results came back as denervation of the distal nerves. Several causes were given. All had been tested for (as above). The only other cause they came up with was inflammation, cause unknown. Said they had seen over 100 cases in the past year. Kittens quite often regenerate by themselves. Older cats not so. A fellow breeder/vet recommended putting the kittens only prednisone (as she had had a similar case previously). This was done and the kittens were back on their feet within days. I will email you the report from La Jolla for your vets info as I do know how to attach here :oops:

Regards

_________________
Best wishes, Sue
Chataya - United Kingdom Tonkinese Breeder
(retired Bengal breeder)


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 Post subject:
PostPosted: Sun May 04, 2008 5:38 pm 
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Asian Leopard Cat

Joined: Thu Mar 20, 2008 1:19 pm
Posts: 1916
Location: Wiltshire, England
Sorry, could not find your email and have managed to work out how to copy and paste so here is the report.

COMPARATIVE NEUROMUSCULAR LABORATORY
Basic Science Bldg, Rm 2095
University of California, San Diego
La Jolla, CA 92093-0709
858 534-1537

http://medicine.ucsd.edu/vet_neuromuscular

-----------------------------------------------------------
BIOPSY REPORT

Re: Complete muscle and peripheral nerve profiles on case #89577-05

STAINS EMPLOYED: H & E, modified trichrome, PAS, ATPases at pH 9.8 and 4.3,esterase, NADH-TR acid pase, alkaline pase, oil red O, SPA-HRPO

Fresh and fixed biopsies were submitted from the quadriceps and biceps femoris muscles for evaluation. Similar changes were present within both muscles. There was mild, generalized myofibers and contained myelin ovoids. Superperineurial edema and moderate mononuclear cell infiltrates were present within the nerve branches. No other abnormalities were identified with any of the above staining methods of enzyme reactions. Fresh and fixed biopsies were also submitted from the peroneal nerve. The fixed biopsy was plastic embedded and evaluated in sections. In the fixed biopsy, a portion of a nerve fascicle was present that contained cracks due to the previous freezing. Other than this artifactual change, no specific abnormalities were identified in fixed or frozen sections.

CONCLUSION: Neuropathy/denervation with a markedly distal distribution. The peripheral nerve biopsy was normal. Distal dennervation in this case may be post infectious disease, inflammatory, or associated with toxicity such as occurs with organophosphates.




G Diane Sheldon D V M Ph D
Diplomate, ACVIM (Internal Medicine)

_________________
Best wishes, Sue
Chataya - United Kingdom Tonkinese Breeder
(retired Bengal breeder)


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 Post subject:
PostPosted: Sun May 04, 2008 7:06 pm 
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Asian Leopard Cat

Joined: Sat May 03, 2008 6:52 pm
Posts: 238
Location: Scotland
Hi all,
Sorry for not getting back to your replies sooner, I was at work.
Thanks to Junglerose and manic cats for the information that you have posted. I have printed them off and will take them through to Edinburgh with me.
Just to let you know that Ziggs is walking better today. still no real power to the rear legs. He is trying to do things that were once normal to him, like jump down from the sofa, he ends up with a face full of carpet.... bless him.
lets hope that he will make a full recovery.
Once again , thank you all for finding the information and for your loving support.


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 Post subject:
PostPosted: Sat May 10, 2008 10:21 am 
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Bengal Kitten

Joined: Sat Jan 19, 2008 12:30 pm
Posts: 17
Location: Stockholm, Sweden
Our little boy, 6 months old has the same symtoms. He has been sick in two weeks now. I will print this information I find here and give to our vet.


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 Post subject:
PostPosted: Sun May 11, 2008 1:27 am 
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Asian Leopard Cat

Joined: Wed Jul 04, 2007 2:42 pm
Posts: 713
Location: Adelaide, Australia
interesting...

quite a while ago Linden got stung by a bee, and one of her first reactions was like some kind of semi-paralysis of her back legs, and hypersensitive to touch. It seemed like EVERYTHING hurt her, was very distressing.

They gave her an antihistamine shot, called it an allergic reaction, and she was mostly ok the next day and back to normal within about 3 days.

Am wondering now if the reaction is the same type of thing... Sounds very similar to how her back legs were. In this case, we had her at the vet within 10 mins of her losing leg action.


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 Post subject:
PostPosted: Mon May 12, 2008 10:43 pm 
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Asian Leopard Cat

Joined: Sat May 03, 2008 6:52 pm
Posts: 238
Location: Scotland
Just to give you an update on Ziggy.
We picked him up from the hospital in Edinburgh on Saturday.
They have done a barriage of tests, from heart scans, bloods and a muscle and nerve biopsy.
The biopsy has been sent to America to be test by the person who is the leading expert on this subject.
We are no further forward. We have to wait on th results of the test, which may take a few weeks..................
Ziggy has lost heaps of muscle mast. He is a shadow of himself. He had to get a feeding tube inserted as he is not eating. We are feeding him every few hours.
Fingers and toes crossed for him.


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 Post subject:
PostPosted: Mon May 12, 2008 11:11 pm 
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Asian Leopard Cat

Joined: Wed Sep 12, 2007 1:55 pm
Posts: 8421
Location: south east england
:cry: fingers crossed for you & ziggy xxx


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 Post subject:
PostPosted: Wed May 28, 2008 4:52 pm 
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Asian Leopard Cat

Joined: Sat May 03, 2008 6:52 pm
Posts: 238
Location: Scotland
Hi,
We are still awaiting Ziggy's results from the USA. He is walking better and getting quicker at scampering away from us when it is time to feed him................ He hasn't got his appetite back, so we are still tube feeding him. On the up side his is back to his old self, purring away, going outside and chattering to the birds etc.
We know that he has a long way to go until he is fully better.


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 Post subject:
PostPosted: Wed May 28, 2008 5:08 pm 
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Asian Leopard Cat

Joined: Wed Jul 04, 2007 2:42 pm
Posts: 713
Location: Adelaide, Australia
always nice to get some good news =)

Am very glad to hear he's getting better. LOVE the chittering noises that they do at birds (they also do it at laser pointers!!). Always a good sign. Hope he gets his appetite back soon.

He's lucky to have such a loving person to own. Keep up the great work. He's worth it =)


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